Analyses of mitochondrial amino acid sequence datasets support the proposal that specimens of Hypodontus macropi from three species of macropodid hosts represent distinct species
dc.contributor.author | Jabbar, A | |
dc.contributor.author | Beveridge, I | |
dc.contributor.author | Mohandas, N | |
dc.contributor.author | Chilton, NB | |
dc.contributor.author | Littlewood, T | |
dc.contributor.author | Jex, AR | |
dc.contributor.author | Gasser, RB | |
dc.date.accessioned | 2020-04-15T10:39:00Z | |
dc.date.available | 2020-04-15T10:39:00Z | |
dc.date.issued | 2013-11-21 | |
dc.date.submitted | 2020-04-06 | |
dc.identifier.citation | Jabbar, A., Beveridge, I., Mohandas, N. et al. Analyses of mitochondrial amino acid sequence datasets support the proposal that specimens of Hypodontus macropi from three species of macropodid hosts represent distinct species. BMC Evol Biol 13, 259 (2013). https://doi.org/10.1186/1471-2148-13-259 | en_US |
dc.identifier.issn | 1471-2148 | |
dc.identifier.doi | 10.1186/1471-2148-13-259 | |
dc.identifier.uri | http://hdl.handle.net/10141/622695 | |
dc.description.abstract | Background: Hypodontus macropi is a common intestinal nematode of a range of kangaroos and wallabies (macropodid marsupials). Based on previous multilocus enzyme electrophoresis (MEE) and nuclear ribosomal DNA sequence data sets, H. macropi has been proposed to be complex of species. To test this proposal using independent molecular data, we sequenced the whole mitochondrial (mt) genomes of individuals of H. macropi from three different species of hosts (Macropus robustus robustus, Thylogale billardierii and Macropus [Wallabia] bicolor) as well as that of Macropicola ocydromi (a related nematode), and undertook a comparative analysis of the amino acid sequence datasets derived from these genomes. Results: The mt genomes sequenced by next-generation (454) technology from H. macropi from the three host species varied from 13,634 bp to 13,699 bp in size. Pairwise comparisons of the amino acid sequences predicted from these three mt genomes revealed differences of 5.8% to 18%. Phylogenetic analysis of the amino acid sequence data sets using Bayesian Inference (BI) showed that H. macropi from the three different host species formed distinct, well-supported clades. In addition, sliding window analysis of the mt genomes defined variable regions for future population genetic studies of H. macropi in different macropodid hosts and geographical regions around Australia. Conclusions: The present analyses of inferred mt protein sequence datasets clearly supported the hypothesis that H. macropi from M. robustus robustus, M. bicolor and T. billardierii represent distinct species. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer Science and Business Media LLC | en_US |
dc.rights | openAccess | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by/2.0/ | |
dc.title | Analyses of mitochondrial amino acid sequence datasets support the proposal that specimens of Hypodontus macropi from three species of macropodid hosts represent distinct species | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journal | BMC Evolutionary Biology | en_US |
dc.identifier.volume | 13 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 259 - 259 | en_US |
pubs.organisational-group | /Natural History Museum | |
pubs.organisational-group | /Natural History Museum/Access control | |
pubs.organisational-group | /Natural History Museum/Access control/Management LS | |
pubs.organisational-group | /Natural History Museum/Science Group | |
pubs.organisational-group | /Natural History Museum/Science Group/Functional groups | |
pubs.organisational-group | /Natural History Museum/Science Group/Functional groups/Research | |
pubs.organisational-group | /Natural History Museum/Science Group/Initiatives | |
pubs.organisational-group | /Natural History Museum/Science Group/Initiatives/Natural Resources and Hazards | |
pubs.organisational-group | /Natural History Museum/Science Group/Life Sciences | |
pubs.organisational-group | /Natural History Museum/Science Group/Life Sciences/Parasites and Vectors | |
pubs.organisational-group | /Natural History Museum/Science Group/Life Sciences/Parasites and Vectors/Parasites and Vectors - Research | |
pubs.organisational-group | /Natural History Museum/Science Group/Science Directorate | |
pubs.organisational-group | /Natural History Museum/Science Group/Science Directorate/Science Directorate | |
dc.embargo | Not known | en_US |
elements.import.author | Jabbar, A | en_US |
elements.import.author | Beveridge, I | en_US |
elements.import.author | Mohandas, N | en_US |
elements.import.author | Chilton, NB | en_US |
elements.import.author | Littlewood, DTJ | en_US |
elements.import.author | Jex, AR | en_US |
elements.import.author | Gasser, RB | en_US |
dc.description.nhm | © 2013 Jabbar et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | en_US |
dc.description.nhm | NHM Repository | |
dc.subject.nhm | Hypodontus macropi | en_US |
dc.subject.nhm | Mitochondrial genome | en_US |
dc.subject.nhm | Kangaroo | en_US |
dc.subject.nhm | Wallaby | en_US |
dc.subject.nhm | Sliding window analysis | en_US |
dc.subject.nhm | Next-generation sequencing | en_US |
dc.subject.nhm | Genetics | en_US |
dc.subject.nhm | Systematics | en_US |
refterms.dateFOA | 2020-04-15T10:39:01Z |