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The evolution and changing ecology of the African hominid oral microbiome

dc.contributor.authorFellows Yates, James A
dc.contributor.authorVelsko, Irina M
dc.contributor.authorAron, Franziska
dc.contributor.authorPosth, Cosimo
dc.contributor.authorHofman, Courtney A
dc.contributor.authorAustin, Rita M
dc.contributor.authorParker, Cody E
dc.contributor.authorMann, Allison E
dc.contributor.authorNägele, Kathrin
dc.contributor.authorArthur, Kathryn Weedman
dc.contributor.authorArthur, John W
dc.contributor.authorBauer, Catherine C
dc.contributor.authorCrevecoeur, Isabelle
dc.contributor.authorCupillard, Christophe
dc.contributor.authorCurtis, Matthew C
dc.contributor.authorDalén, Love
dc.contributor.authorDíaz-Zorita Bonilla, Marta
dc.contributor.authorDíez Fernández-Lomana, J Carlos
dc.contributor.authorDrucker, Dorothée G
dc.contributor.authorEscribano Escrivá, Elena
dc.contributor.authorFrancken, Michael
dc.contributor.authorGibbon, Victoria E
dc.contributor.authorGonzález Morales, Manuel R
dc.contributor.authorGrande Mateu, Ana
dc.contributor.authorHarvati, Katerina
dc.contributor.authorHenry, Amanda G
dc.contributor.authorHumphrey, Louise
dc.contributor.authorMenéndez, Mario
dc.contributor.authorMihailović, Dušan
dc.contributor.authorPeresani, Marco
dc.contributor.authorRodríguez Moroder, Sofía
dc.contributor.authorRoksandic, Mirjana
dc.contributor.authorRougier, Hélène
dc.contributor.authorSázelová, Sandra
dc.contributor.authorStock, Jay T
dc.contributor.authorStraus, Lawrence Guy
dc.contributor.authorSvoboda, Jiří
dc.contributor.authorTeßmann, Barbara
dc.contributor.authorWalker, Michael J
dc.contributor.authorPower, Robert C
dc.contributor.authorLewis, Cecil M
dc.contributor.authorSankaranarayanan, Krithivasan
dc.contributor.authorGuschanski, Katerina
dc.contributor.authorWrangham, Richard W
dc.contributor.authorDewhirst, Floyd E
dc.contributor.authorSalazar-García, Domingo C
dc.contributor.authorKrause, Johannes
dc.contributor.authorHerbig, Alexander
dc.contributor.authorWarinner, Christina
dc.date.accessioned2025-02-04T10:07:33Z
dc.date.available2025-02-04T10:07:33Z
dc.date.issued2021-05-18
dc.identifier.citationJ.A. Fellows Yates, I.M. Velsko, F. Aron, C. Posth, C.A. Hofman, R.M. Austin, C.E. Parker, A.E. Mann, K. Nägele, K.W. Arthur, J.W. Arthur, C.C. Bauer, I. Crevecoeur, C. Cupillard, M.C. Curtis, L. Dalén, M. Díaz-Zorita Bonilla, J.C. Díez Fernández-Lomana, D.G. Drucker, E. Escribano Escrivá, M. Francken, V.E. Gibbon, M.R. González Morales, A. Grande Mateu, K. Harvati, A.G. Henry, L. Humphrey, M. Menéndez, D. Mihailović, M. Peresani, S. Rodríguez Moroder, M. Roksandic, H. Rougier, S. Sázelová, J.T. Stock, L.G. Straus, J. Svoboda, B. Teßmann, M.J. Walker, R.C. Power, C.M. Lewis, K. Sankaranarayanan, K. Guschanski, R.W. Wrangham, F.E. Dewhirst, D.C. Salazar-García, J. Krause, A. Herbig, C. Warinner, The evolution and changing ecology of the African hominid oral microbiome, Proc. Natl. Acad. Sci. U.S.A. 118 (20) e2021655118, https://doi.org/10.1073/pnas.2021655118 (2021).en_US
dc.identifier.issn0027-8424
dc.identifier.doi10.1073/pnas.2021655118
dc.identifier.urihttp://hdl.handle.net/10141/623176
dc.description.abstractSignificance The microbiome plays key roles in human health, but little is known about its evolution. We investigate the evolutionary history of the African hominid oral microbiome by analyzing dental biofilms of humans and Neanderthals spanning the past 100,000 years and comparing them with those of chimpanzees, gorillas, and howler monkeys. We identify 10 core bacterial genera that have been maintained within the human lineage and play key biofilm structural roles. However, many remain understudied and unnamed. We find major taxonomic and functional differences between the oral microbiomes of Homo and chimpanzees but a high degree of similarity between Neanderthals and modern humans, including an apparent Homo-specific acquisition of starch digestion capability in oral streptococci, suggesting microbial coadaptation with host diet.en_US
dc.language.isoenen_US
dc.publisherProceedings of the National Academy of Sciencesen_US
dc.rightsopenAccessen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.en
dc.rights.uri
dc.titleThe evolution and changing ecology of the African hominid oral microbiomeen_US
dc.typeJournal Articleen_US
dc.identifier.eissn1091-6490
dc.identifier.journalProceedings of the National Academy of Sciencesen_US
dc.date.updated2025-01-07T13:45:29Z
dc.identifier.volume118en_US
dc.identifier.issue20en_US
dc.identifier.startpagee2021655118-en_US
elements.import.authorFellows Yates, James A
elements.import.authorVelsko, Irina M
elements.import.authorAron, Franziska
elements.import.authorPosth, Cosimo
elements.import.authorHofman, Courtney A
elements.import.authorAustin, Rita M
elements.import.authorParker, Cody E
elements.import.authorMann, Allison E
elements.import.authorNägele, Kathrin
elements.import.authorArthur, Kathryn Weedman
elements.import.authorArthur, John W
elements.import.authorBauer, Catherine C
elements.import.authorCrevecoeur, Isabelle
elements.import.authorCupillard, Christophe
elements.import.authorCurtis, Matthew C
elements.import.authorDalén, Love
elements.import.authorDíaz-Zorita Bonilla, Marta
elements.import.authorDíez Fernández-Lomana, J Carlos
elements.import.authorDrucker, Dorothée G
elements.import.authorEscribano Escrivá, Elena
elements.import.authorFrancken, Michael
elements.import.authorGibbon, Victoria E
elements.import.authorGonzález Morales, Manuel R
elements.import.authorGrande Mateu, Ana
elements.import.authorHarvati, Katerina
elements.import.authorHenry, Amanda G
elements.import.authorHumphrey, Louise
elements.import.authorMenéndez, Mario
elements.import.authorMihailović, Dušan
elements.import.authorPeresani, Marco
elements.import.authorRodríguez Moroder, Sofía
elements.import.authorRoksandic, Mirjana
elements.import.authorRougier, Hélène
elements.import.authorSázelová, Sandra
elements.import.authorStock, Jay T
elements.import.authorStraus, Lawrence Guy
elements.import.authorSvoboda, Jiří
elements.import.authorTeßmann, Barbara
elements.import.authorWalker, Michael J
elements.import.authorPower, Robert C
elements.import.authorLewis, Cecil M
elements.import.authorSankaranarayanan, Krithivasan
elements.import.authorGuschanski, Katerina
elements.import.authorWrangham, Richard W
elements.import.authorDewhirst, Floyd E
elements.import.authorSalazar-García, Domingo C
elements.import.authorKrause, Johannes
elements.import.authorHerbig, Alexander
elements.import.authorWarinner, Christina
dc.description.nhmCopyright © 2021 the Author(s). Published by PNAS. This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND). The attached file is the published version of the article.en_US
dc.description.nhmNHM Repository
dc.subject.nhmdental calculusen_US
dc.subject.nhmmicrobiomeen_US
dc.subject.nhmNeanderthalen_US
dc.subject.nhmprimateen_US
dc.subject.nhmsalivary amylaseen_US
refterms.dateFOA2025-02-04T10:07:35Z


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